The study was conducted to evaluate the effect of seed sett sizes and planting density on the tuber size and yields of yam. The treatments were arranged in a split-split plot design with two premium Dioscorea rotundata varieties (Pona and Dente) as main plot. Seed sett sizes (farmers' sett size 350 g, half farmers' sett size 175g) as subplot and Planting density (6944 plt/ha; 8333 plt/ha; 10417plt/ha; 13889 plt/ha; 20833 plt/ha) as sub-sub plot in 2014. Minisetts (50 g) a popular yam multiplication technique was added in 2015.