Tigernut production in Ghana is associated with high levels of manual labour and little use of machinery. Men and women in tigernut farming play a significant role in the various farm tasks associated with tigernut (Cyperus esculentus) production in the Eastern Region of Ghana. A survey of 100 tigernut farmers (50 male and 50 female) in Aduamoa in the Eastern Region of Ghana was carried out to ascertain the leading occupational hazards and injuries faced by the tigernut farmers during preplanting and planting, post-planting, harvesting and post-harvest operations.